Pituitary-Adrenal Functions in a Hereditary Hypothyroid (rdw) Rat
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چکیده
منابع مشابه
Pituitary-adrenal functions in a hereditary hypothyroid (rdw) rat.
The rdw rat is a hereditary hypothyroid strain isolated from Wistar-Imamichi rats. In the present study, adrenocorticotropic hormone (ACTH) and corticosterone responses to restraint stress (120 min) were examined in rdw adult male rats. ACTH response to restraint stress was higher in rdw rats than in hetero control rats. The plasma concentrations of corticosterone were lower in rdw rats than in...
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Proteins having relations to hereditary dwarfism of the rdw rat (gene symbol: rdw) were searched for in various tissues of the rat with an improved two-dimensional gel electrophoresis technique followed by immunoblotting and microsequencing. Tissues inspected were cerebral cortex, cerebellum, brain trunk, hypothalamus, pituitary, thyroid gland, liver, testis, spleen, and thymus. Only pituitary ...
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The discharge of cholesterol, ascorbic acid, and histologically demonstrable lipides from the adrenal glands is generally regarded as evidence of increased activity of these glands during stress (l-5). These changes were also produced upon injection of purified corticotropin (6). However, in the detailed study of Fortier et al. (7) it was shown that corticotropin (ACTH) alone cannot account for...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2010
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.59.95